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This is Toronto Wound Care in Toronto, Ontario

Treating Chronic Non-Healing Wounds/Diabetic Wounds using Hyperbaric Oxygen Therapy, Medical Director Dr. C. Anne Mildon

Non-healing wounds are those which fail to heal within a reasonable time frame despite adequate management. Although multifactorial in aetiology, these wounds are typically hypoxic which is where HBOT becomes very effective. The rationale for treatment of chronic non-healing wounds with HBOT uses the known secondary mechanisms of action. HBOT leads to improved angiogenesis through a multifactorial mechanism. First, fibroblast proliferation and collagen synthesis are oxygen dependent, and collagen is the foundational matrix for angiogenesis. In addition, HBOT likely stimulates growth factors, particularly vascular endothelial growth factor (VEGF), involving angiogenesis and other mediators of the wound healing process. Hyperbaric oxygen also has been shown to have direct and indirect antimicrobial activity; in particular, it increases intracellular leukocyte killing. Decreased oedema due to systemic vasoconstriction allows better diffusion of oxygen and nutrients through tissues while also relieving pressure on the surrounding vessels and structures.
Non-healing wounds where HBOT has been successfully used include diabetic foot ulcers, venous and arterial insufficiency ulcers. Diabetic lower extremity ulcers have been the focus of most wound research in hyperbaric medicine, since the aetiology of these wounds is multifactorial, and HBOT can address many of these factors. Several randomised controlled clinical trials have proven the beneficial effects of HBOT for the treatment of diabetic lower extremity wounds, apart from many prospective, non-controlled clinical and retrospective studies.
HBOT in diabetic wounds is used in conjunction with other wound management techniques including wound debridement, dressings, pressure-relieving strategies, appropriate glycaemic control, and nutrition and antibiotic management.


Highly Regarded, Trusted Sources

Curbing Inflammation in Skin Wound Healing

Role of HBOT in Treating Ischaemic Diabetic Lower Extremeity Ulcers

Hyperbaric Oxygen for the Treatment of Diabetic Ulcers

What is Hyperbaric Oxygen Therapy?

A Brief Summary

Hyperbaric oxygen therapy is a medical treatment which enhances the body's
natural healing processes by inhalation of 100% medical grade oxygen in a total body chamber,
where atmospheric pressure is increased and controlled. it is used for a wide variety
of treatments usually as part of an overall medcial care plan.
Under normal circumstances, oxygen is transported throughout the body only by red blood cells. With HBOT, oxygen is
Dissolved into all of the body's fluids, the plasma, the central nervous system fluids, the lympH, and the bone and can be
carried to areas where circulation is diminished or blocked. In this way, extra oxygen can reach all of the damaged
tissues and the body can support its own healing process. THe increased oxygen greatly enhances the ability of white
blood cells to kill bacteria, reduces swelling and allows new blood vessels to grow more rapidly
it is a simple, non-invasive treatment.
  • Health and cheerfulness naturally beget each other

    - Joseph Addison -
  • The greatest wealth is health

    - Virgil -
  • Health is a relationship between you and your body.

    - Terri Guillemets -

Why Toronto Wound Care?

Toronto's Premier Hyperbaric Oxygen Therapy Centre

  • Qualified experienced staff including an Orthomolecular Nutritionist
  • Five state-of-the-art, air-break equipped, mono-place chambers
  • Clean, spacious, family friendly centre including a full kitchen, quiet room, and TV lounge with childrens' toys
  • VOC (volatile organic compound) free centre including no perfumes, harmful checmicals etc.
  • All chamber bedding (organic) and patient scrubs made from 100% cotton material, washed on-site using hypoallergenic, scent-free soap
  • Great drinking water - Remineralized Reverse Osmosis Water
  • Wheelchair accessible washrooms
  • Efficient & fast patient intake
  • On-time chamber bookings, we value time as an irreplacable commodity
  • Free WiFi throughout the centre
  • Free Parking out front
Treatments Performed
Years Operating
Dollars for Parking
  • Health and cheerfulness naturally beget each other

    - Joseph Addison -
  • The greatest wealth is health

    - Virgil -
  • Health is a relationship between you and your body.

    - Terri Guillemets -

Contact Us

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136B Cartwright Avenue Toronto, Ontario, Canada M6A 1V2